Abstract Search

ea0044oc5.4 | Diabetes Mellitus and Metabolism | SFEBES2016

Two contrasting cases of spontaneous severe hypoglycaemia secondary to anti-insulin antibodies (Insulin Autoimmune Syndrome / Hirata disease)

Moorthy Myuri , Freudenthal Bernard , Church David , Kisalu Judith , Woolman Emma , Hale Amy , Beynon Huw , Karra Efthimia , Cohen Mark , Khoo Bernard

IAS is a very rare condition in which anti-insulin antibodies carry high concentrations of insulin in suspension in circulation. Hypoglycaemia occurs when insulin is released from the antibodies during fasting or post-prandially.We present two cases. Patient-A is a 52-year old Thai obese female, with acanthosis nigricans and a strong family history of T2DM. Patient-B is a 28 year-old normal- BMI Caucasian female with an unremarkable history. None of the ...

0 shares

ea0069p1 | Poster Presentations | SFENCC2020

Two contrasting cases of spontaneous severe hypoglycaemia secondary to anti-insulin antibodies (Insulin Autoimmune Syndrome / Hirata disease)

Eltayeb Randa , Banu Zeenat , Aziz Umaira , Eldigair Hiba , Kisalu Judith , Woolman Emma , Beynon Huw , Church David , Kenneth Robert , Khoo Bernard , Cohen Mark , Karra Efthimia

Insulin Autoimmune Syndrome (IAS)/Hirata disease is a very rare condition in which anti-insulin antibodies result in accumulation of high circulating concentrations of insulin in complexes. Hypoglycaemia in IAS occurs when insulin is released from the antibodies during fasting. We present two contrasting cases of Hirata disease. Both patients presented with symptomatic hypoglycaemia. Patient-A is a 52-year old obese Thai female, with acanthosis nigricans and a strong family hi...

1 shares

Endocrine Abstracts

Two contrasting cases of spontaneous severe hypoglycaemia secondary to anti-insulin antibodies (Insulin Autoimmune Syndrome / Hirata disease)

Two contrasting cases of spontaneous severe hypoglycaemia secondary to anti-insulin antibodies (Insulin Autoimmune Syndrome / Hirata disease)

BiosciAbstracts